Table 2

Composition of interstitial fluid in tumors

Tumor type

Host

Protein, mg/ml

COP, mm Hg

pH

Lactic acid, mg/l

Reference


TIF

Subcutis

Plasma

TIF

Subcutis

Plasma

TIF

Plasma (arterial)

TIF

Plasma


Carcinoma (Walker 256)

Rat

32 ± 1

41 ± 2

48 ± 1

7.044 ±0.044

7.313 ± 0.041

16.1 ± 1.1

9.5 ± 0.9

[41,95]


Mammary carcinoma

Mouse

54

55 - 60

[40]


Carcinoma (Walker 256)

Rat

6.98 ± 0.13

15

15

[70]


Colon adenocarcinoma (LS174T)

Mouse

16.7 ± 3.0

[43]

Small cell lung carcinoma (54A)

21.1 ± 2.8

8.2 ±2.3

20.0 ± 1.6


Mammary carcinoma (chemically induced)

Rat

44.7

54.9

16.6 ± 1.0

13.8 ±1.0

20.5 ±0.8

[61]


COP: Colloid osmotic pressure, TIF: Tumor interstitial fluid. Empty cells in table: Value not determined

Wiig et al. Fibrogenesis & Tissue Repair 2010 3:12   doi:10.1186/1755-1536-3-12

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