Table 2 |
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Composition of interstitial fluid in tumors |
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Tumor type |
Host |
Protein, mg/ml |
COP, mm Hg |
pH |
Lactic acid, mg/l |
Reference |
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|
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|
TIF |
Subcutis |
Plasma |
TIF |
Subcutis |
Plasma |
TIF |
Plasma (arterial) |
TIF |
Plasma |
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|
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|
Carcinoma (Walker 256) |
Rat |
32 ± 1 |
41 ± 2 |
48 ± 1 |
7.044 ±0.044 |
7.313 ± 0.041 |
16.1 ± 1.1 |
9.5 ± 0.9 |
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|
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Mammary carcinoma |
Mouse |
54 |
55 - 60 |
[40] |
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|
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Carcinoma (Walker 256) |
Rat |
6.98 ± 0.13 |
15 |
15 |
[70] |
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|
|
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Colon adenocarcinoma (LS174T) |
Mouse |
16.7 ± 3.0 |
[43] |
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Small cell lung carcinoma (54A) |
21.1 ± 2.8 |
8.2 ±2.3 |
20.0 ± 1.6 |
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|
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Mammary carcinoma (chemically induced) |
Rat |
44.7 |
54.9 |
16.6 ± 1.0 |
13.8 ±1.0 |
20.5 ±0.8 |
[61] |
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|
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COP: Colloid osmotic pressure, TIF: Tumor interstitial fluid. Empty cells in table: Value not determined |
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|
Wiig et al. Fibrogenesis & Tissue Repair 2010 3:12 doi:10.1186/1755-1536-3-12 |
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