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1.

691
Accesses

Review   Open Access Highly Accessed

The multifaceted role of pirfenidone and its novel targets

José Macías-Barragán, Ana Sandoval-Rodríguez, Jose Navarro-Partida, Juan Armendáriz-Borunda Fibrogenesis & Tissue Repair 2010, 3:16 (1 September 2010)

Abstract | Full text | PDF | PubMed

2.

615
Accesses

Review   Open Access Highly Accessed

Molecular and cellular mechanisms of pulmonary fibrosis

Nevins W Todd, Irina G Luzina, Sergei P Atamas Fibrogenesis & Tissue Repair 2012, 5:11 (23 July 2012)

Abstract | Full text | PDF | PubMed

3.

472
Accesses

Review   Open Access Highly Accessed

Redox mechanisms in hepatic chronic wound healing and fibrogenesis

Erica Novo, Maurizio Parola Fibrogenesis & Tissue Repair 2008, 1:5 (13 October 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

4.

454
Accesses

Review   Open Access Highly Accessed

Plasma and cellular fibronectin: distinct and independent functions during tissue repair

Wing S To, Kim S Midwood Fibrogenesis & Tissue Repair 2011, 4:21 (16 September 2011)

Abstract | Full text | PDF | PubMed

5.

450
Accesses

Review   Open Access Highly Accessed

Focus on collagen: in vitro systems to study fibrogenesis and antifibrosis _ state of the art

Clarice ZC Chen, Michael Raghunath Fibrogenesis & Tissue Repair 2009, 2:7 (15 December 2009)

Abstract | Full text | PDF | PubMed

6.

449
Accesses

Review   Open Access Highly Accessed

Cardiac fibroblasts, fibrosis and extracellular matrix remodeling in heart disease

Dong Fan, Abhijit Takawale, Jiwon Lee, Zamaneh Kassiri Fibrogenesis & Tissue Repair 2012, 5:15 (3 September 2012)

Abstract | Full text | PDF | PubMed

7.

375
Accesses

Review   Open Access Highly Accessed

HDAC inhibitors in experimental liver and kidney fibrosis

Katrien Van Beneden, Inge Mannaerts, Marina Pauwels, Christiane Van den Branden, Leo A van Grunsven Fibrogenesis & Tissue Repair 2013, 6:1 (2 January 2013)

Abstract | Full text | PDF | PubMed

8.

325
Accesses

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Heat shock protein 27 (HSP27): biomarker of disease and therapeutic target

Aparna Vidyasagar, Nancy A Wilson, Arjang Djamali Fibrogenesis & Tissue Repair 2012, 5:7 (7 May 2012)

Abstract | Full text | PDF | PubMed

9.

308
Accesses

Review   Open Access

Function and fate of myofibroblasts after myocardial infarction

Neil A Turner, Karen E Porter Fibrogenesis & Tissue Repair 2013, 6:5 (1 March 2013)

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10.

305
Accesses

Research   Open Access

Serum amyloid P ameliorates radiation-induced oral mucositis and fibrosis

Lynne A Murray, Michael S Kramer, David P Hesson, Brynmor A Watkins, Edward G Fey, Rochelle L Argentieri, Furquan Shaheen, Darryl A Knight, Stephen T Sonis Fibrogenesis & Tissue Repair 2010, 3:11 (5 July 2010)

Abstract | Full text | PDF | PubMed

11.

303
Accesses

Research   Open Access Highly Accessed

Cooperative interaction of CTGF and TGF-β in animal models of fibrotic disease

Qingjian Wang, William Usinger, Blake Nichols, Julia Gray, Leon Xu, Todd W Seeley, Mitch Brenner, Guangjie Guo, Weihua Zhang, Noelynn Oliver, Al Lin, David Yeowell Fibrogenesis & Tissue Repair 2011, 4:4 (1 February 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

12.

302
Accesses

Review   Open Access

Animal models for investigating chronic pancreatitis

Alexander A Aghdassi, Julia Mayerle, Sandra Christochowitz, Frank U Weiss, Matthias Sendler, Markus M Lerch Fibrogenesis & Tissue Repair 2011, 4:26 (1 December 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

13.

298
Accesses

Review   Open Access Highly Accessed

Achievements and challenges in bioartificial kidney development

Farah Tasnim, Rensheng Deng, Min Hu, Sean Liour, Yao Li, Ming Ni, Jackie Y Ying, Daniele Zink Fibrogenesis & Tissue Repair 2010, 3:14 (10 August 2010)

Abstract | Full text | PDF | PubMed

14.

297
Accesses

Research   Open Access

Autologous keratinocyte suspension in platelet concentrate accelerates and enhances wound healing -- a prospective randomized clinical trial on skin graft donor sites: platelet concentrate and keratinocytes on donor sites

Samia Guerid, Salim E Darwiche, Mette M Berger, Messod Benathan, Wassim Raffoul Fibrogenesis & Tissue Repair 2013, 6:8 (9 April 2013)

Abstract | Provisional PDF | PubMed

15.

297
Accesses

Research   Open Access

Biglycan fragmentation in pathologies associated with extracellular matrix remodeling by matrix metalloproteinases

Federica Genovese, Natasha Barascuk, Lise Larsen, Martin Røssel Larsen, Arkadiusz Nawrocki, Yili Li, Qinlong Zheng, Jianxia Wang, Sanne Skovgård Veidal, Diana Julie Leeming, Morten Asser Karsdal Fibrogenesis & Tissue Repair 2013, 6:9 (1 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

16.

291
Accesses

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Toll-like receptor 4 signaling in liver injury and hepatic fibrogenesis

Jinsheng Guo, Scott L Friedman Fibrogenesis & Tissue Repair 2010, 3:21 (21 October 2010)

Abstract | Full text | PDF | PubMed

17.

289
Accesses

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Genomics and proteomics in liver fibrosis and cirrhosis

Rebekka A Hannivoort, Virginia Hernandez-Gea, Scott L Friedman Fibrogenesis & Tissue Repair 2012, 5:1 (3 January 2012)

Abstract | Full text | PDF | PubMed

18.

284
Accesses

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Endothelial progenitor cells and integrins: adhesive needs

Francisco Caiado, Sérgio Dias Fibrogenesis & Tissue Repair 2012, 5:4 (12 March 2012)

Abstract | Full text | PDF | PubMed

19.

263
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Research   Open Access Highly Accessed

Epithelial-mesenchymal transition in primary human bronchial epithelial cells is Smad-dependent and enhanced by fibronectin and TNF-α

Joana Câmara, Gabor Jarai Fibrogenesis & Tissue Repair 2010, 3:2 (5 January 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

20.

262
Accesses

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Mesenchymal stem cells: from experiment to clinic

William R Otto, Nicholas A Wright Fibrogenesis & Tissue Repair 2011, 4:20 (8 September 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

21.

261
Accesses

Research   Open Access

Platelet-derived growth factor alpha and beta receptors have overlapping functional activities towards fibroblasts

Johanna Donovan, Xu Shiwen, Jill Norman, David Abraham Fibrogenesis & Tissue Repair 2013, 6:10 (10 May 2013)

Abstract | Provisional PDF | PubMed

22.

259
Accesses

Review   Open Access Highly Accessed

Experimental obstructive cholestasis: the wound-like inflammatory liver response

María-Angeles Aller, Jorge-Luis Arias, Jose García-Domínguez, Jose-Ignacio Arias, Manuel Durán, Jaime Arias Fibrogenesis & Tissue Repair 2008, 1:6 (3 November 2008)

Abstract | Full text | PDF | PubMed

23.

242
Accesses

Review   Open Access

Diabetic angiopathy and angiogenic defects

Ling Xu, Keizo Kanasaki, Munehiro Kitada, Daisuke Koya Fibrogenesis & Tissue Repair 2012, 5:13 (1 August 2012)

Abstract | Full text | PDF | PubMed

24.

224
Accesses

Research   Open Access

Cyclosporin A reduces matrix metalloproteinases and collagen expression in dermal fibroblasts from regenerative FOXN1 deficient (nude) mice

Barbara Gawronska-Kozak, Heather Kirk-Ballard Fibrogenesis & Tissue Repair 2013, 6:7 (2 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

25.

219
Accesses

Research   Open Access

Altered monocyte and fibrocyte phenotype and function in scleroderma interstitial lung disease: reversal by caveolin-1 scaffolding domain peptide

Elena Tourkina, Michael Bonner, James Oates, Ann Hofbauer, Mathieu Richard, Sergei Znoyko, Richard P Visconti, Jing Zhang, Corey M Hatfield, Richard M Silver, Stanley Hoffman Fibrogenesis & Tissue Repair 2011, 4:15 (1 July 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

26.

216
Accesses

Research   Open Access

Secreted protein acidic and rich in cysteine (SPARC) is upregulated by transforming growth factor (TGF)-β and is required for TGF-β-induced hydrogen peroxide production in fibroblasts

Saiko Shibata, Junichi Ishiyama Fibrogenesis & Tissue Repair 2013, 6:6 (21 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

27.

212
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Possible mechanisms of kidney repair

Paola Romagnani, Raghu Kalluri Fibrogenesis & Tissue Repair 2009, 2:3 (26 June 2009)

Abstract | Full text | PDF | PubMed

28.

197
Accesses

Proceedings   Open Access

Reversibility of liver fibrosis

Antonella Pellicoro, Prakash Ramachandran, John P Iredale Fibrogenesis & Tissue Repair 2012, 5(Suppl 1):S26 (6 June 2012)

Abstract | Full text | PDF

29.

198
Accesses

Review   Open Access

Common threads in cardiac fibrosis, infarct scar formation, and wound healing

Michael P Czubryt Fibrogenesis & Tissue Repair 2012, 5:19 (1 November 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

30.

198
Accesses

Research   Open Access

Elevated transforming growth factor β and mitogen-activated protein kinase pathways mediate fibrotic traits of Dupuytren's disease fibroblasts

Carola Krause, Peter Kloen, Peter ten Dijke Fibrogenesis & Tissue Repair 2011, 4:14 (28 June 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

31.

195
Accesses

Review   Open Access

Emerging role of the interleukin (IL)-33/ST2 axis in gut mucosal wound healing and fibrosis

Loris R Lopetuso, Franco Scaldaferri, Theresa T Pizarro Fibrogenesis & Tissue Repair 2012, 5:18 (14 October 2012)

Abstract | Full text | PDF | PubMed

32.

194
Accesses

Review   Open Access

Elevation of the antifibrotic peptide N-acetyl-seryl-aspartyl-lysyl-proline: a blood pressure-independent beneficial effect of angiotensin I-converting enzyme inhibitors

Megumi Kanasaki, Takako Nagai, Munehiro Kitada, Daisuke Koya, Keizo Kanasaki Fibrogenesis & Tissue Repair 2011, 4:25 (30 November 2011)

Abstract | Full text | PDF | PubMed

33.

192
Accesses

Short review   Open Access

Interstitial fluid: the overlooked component of the tumor microenvironment?

Helge Wiig, Olav Tenstad, Per Iversen, Raghu Kalluri, Rolf Bjerkvig Fibrogenesis & Tissue Repair 2010, 3:12 (23 July 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

34.

187
Accesses

Proceedings   Open Access

Functional role of intrahepatic monocyte subsets for the progression of liver inflammation and liver fibrosis in vivo

Frank Tacke Fibrogenesis & Tissue Repair 2012, 5(Suppl 1):S27 (6 June 2012)

Abstract | Full text | PDF

35.

179
Accesses

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Role of stem/progenitor cells in reparative disorders

Thavaneetharajah Pretheeban, Dario R Lemos, Benjamin Paylor, Regan-Heng Zhang, Fabio M Rossi Fibrogenesis & Tissue Repair 2012, 5:20 (27 December 2012)

Abstract | Full text | PDF | PubMed

36.

178
Accesses

Proceedings   Open Access

CTGF is a central mediator of tissue remodeling and fibrosis and its inhibition can reverse the process of fibrosis

Kenneth E Lipson, Carol Wong, Yuchin Teng, Suzanne Spong Fibrogenesis & Tissue Repair 2012, 5(Suppl 1):S24 (6 June 2012)

Abstract | Full text | PDF

37.

175
Accesses

Review   Open Access

Epithelial to mesenchymal transition as a biomarker in renal fibrosis: are we ready for the bedside?

Pierre Galichon, Alexandre Hertig Fibrogenesis & Tissue Repair 2011, 4:11 (6 April 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

38.

174
Accesses

Research   Open Access

Assessment of proteolytic degradation of the basement membrane: a fragment of type IV collagen as a biochemical marker for liver fibrosis

Sanne S Veidal, Morten A Karsdal, Arkadiusz Nawrocki, Martin R Larsen, Yueqin Dai, Qinlong Zheng, Per Hägglund, Ben Vainer, Helene Skjøt-Arkil, Diana J Leeming Fibrogenesis & Tissue Repair 2011, 4:22 (5 October 2011)

Abstract | Full text | PDF | PubMed

39.

172
Accesses

Review   Open Access Highly Accessed

Cell-matrix interactions in dermal repair and scarring

Beate Eckes, Roswitha Nischt, Thomas Krieg Fibrogenesis & Tissue Repair 2010, 3:4 (11 March 2010)

Abstract | Full text | PDF | PubMed

40.

165
Accesses

Review   Open Access

Angiogenesis and chronic kidney disease

Yohei Maeshima, Hirofumi Makino Fibrogenesis & Tissue Repair 2010, 3:13 (5 August 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

41.

165
Accesses

Review   Open Access

The role of renin angiotensin system inhibition in kidney repair

Irene M van der Meer, Paolo Cravedi, Giuseppe Remuzzi Fibrogenesis & Tissue Repair 2010, 3:7 (4 May 2010)

Abstract | Full text | PDF | PubMed

42.

161
Accesses

Research   Open Access

Centrilobular emphysema combined with pulmonary fibrosis results in improved survival

Nevins W Todd, Jean Jeudy, Sachin Lavania, Teri J Franks, Jeffrey R Galvin, Janaki Deepak, Edward J Britt, Sergei P Atamas Fibrogenesis & Tissue Repair 2011, 4:6 (15 February 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

43.

157
Accesses

Research   Open Access

Investigation of Toll-like receptors in the pathogenesis of fibrotic and granulomatous disorders: a bronchoalveolar lavage study

Giorgos A Margaritopoulos, Katerina M Antoniou, Kostas Karagiannis, Katerina D Samara, Ismini Lasithiotaki, Evi Vassalou, Rena Lymbouridou, Helen Koutala, Nikos M Siafakas Fibrogenesis & Tissue Repair 2010, 3:20 (11 October 2010)

Abstract | Full text | PDF | PubMed

44.

157
Accesses

Research   Open Access

Impaired dermal wound healing in discoidin domain receptor 2-deficient mice associated with defective extracellular matrix remodeling

Elvira Olaso, Hsin-Chieh Lin, Li-Hsien Wang, Scott L Friedman Fibrogenesis & Tissue Repair 2011, 4:5 (2 February 2011)

Abstract | Full text | PDF | PubMed

45.

157
Accesses

Research   Open Access

N-acetylcysteine for the prevention of stricture after circumferential endoscopic submucosal dissection of the esophagus: a randomized trial in a porcine model

Maximilien Barret, Frédéric Batteux, Frédéric Beuvon, Luigi Mangialavori, Ariane Chryssostalis, Carlos Pratico, Stanislas Chaussade, Frédéric Prat Fibrogenesis & Tissue Repair 2012, 5:8 (28 May 2012)

Abstract | Full text | PDF | PubMed

46.

156
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Research   Open Access

Mast cells and hypoxia drive tissue metaplasia and heterotopic ossification in idiopathic arthrofibrosis after total knee arthroplasty

Theresa A Freeman, Javad Parvizi, Craig J Dela Valle, Marla J Steinbeck Fibrogenesis & Tissue Repair 2010, 3:17 (1 September 2010)

Abstract | Full text | PDF | PubMed

47.

156
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Research   Open Access Highly Accessed

Procollagen type I N-terminal propeptide (PINP) is a marker for fibrogenesis in bile duct ligation-induced fibrosis in rats

Sanne Veidal, Efstathios Vassiliadis, Anne-Christine Bay-Jensen, Gervais Tougas, Ben Vainer, Morten Karsdal Fibrogenesis & Tissue Repair 2010, 3:5 (1 April 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

48.

156
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Research   Open Access

Comparison of gene expression profiling between lung fibrotic and emphysematous tissues sampled from patients with combined pulmonary fibrosis and emphysema

Masayuki Hanaoka, Michiko Ito, Yunden Droma, Atsuhito Ushiki, Yoshiaki Kitaguchi, Masanori Yasuo, Keishi Kubo Fibrogenesis & Tissue Repair 2012, 5:17 (1 October 2012)

Abstract | Full text | PDF | PubMed

49.

156
Accesses

Proceedings   Open Access

Origin of myofibroblasts in liver fibrosis

David A Brenner, Tatiana Kisseleva, David Scholten, Yong Han Paik, Keiko Iwaisako, Sayaka Inokuchi, Bernd Schnabl, Ekihiro Seki, Samuele De Minicis, Christoph Oesterreicher, Kojiro Taura Fibrogenesis & Tissue Repair 2012, 5(Suppl 1):S17 (6 June 2012)

Abstract | Full text | PDF

50.

152
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Proceedings   Open Access

Connective tissue growth factor in tumor pathogenesis

Annica Jacobson, Janet L Cunningham Fibrogenesis & Tissue Repair 2012, 5(Suppl 1):S8 (6 June 2012)

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