Myofibroblast origins. The main myofibroblast progenitor after injury of different tissues appears to be locally residing fibroblasts. Indeed, various cell types can acquire a myofibroblastic phenotype; these diverse origins lead to distinct myofibroblast sub-populations. EMT: epithelial- and endothelial-to-mesenchymal transition.
Micallef et al. Fibrogenesis & Tissue Repair 2012 5(Suppl 1):S5 doi:10.1186/1755-1536-5-S1-S5