This article is part of the supplement: Proceedings of Fibroproliferative disorders: from biochemical analysis to targeted therapies
Proteomics approaches to fibrotic disorders
NHLBI Proteomics Core , National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health, 10 Center Drive, Bethesda, MD 20892, USA
Fibrogenesis & Tissue Repair 2012, 5(Suppl 1):S10 doi:10.1186/1755-1536-5-S1-S10Published: 6 June 2012
This review provides an introduction to mass spectrometry based proteomics and discusses several proteomics approaches that are relevant in understanding the pathophysiology of fibrotic disorders and the approaches that are frequently used in biomarker discovery.