This article is part of the supplement: Proceedings of Fibroproliferative disorders: from biochemical analysis to targeted therapies

Open Access Proceedings

Proteomics approaches to fibrotic disorders

Marjan Gucek

Author Affiliations

NHLBI Proteomics Core , National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health, 10 Center Drive, Bethesda, MD 20892, USA

Fibrogenesis & Tissue Repair 2012, 5(Suppl 1):S10 doi:10.1186/1755-1536-5-S1-S10

Published: 6 June 2012

Abstract

This review provides an introduction to mass spectrometry based proteomics and discusses several proteomics approaches that are relevant in understanding the pathophysiology of fibrotic disorders and the approaches that are frequently used in biomarker discovery.