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Open Access Editorial

Cardiac myofibroblasts: cells out of balance. A new thematic series

Ian M C Dixon

Author Affiliations

Principal Investigator, Laboratory of Molecular Cardiology, Department of Physiology, Faculty of Medicine and the Institute of Cardiovascular Sciences, St. Boniface General Hospital Research Centre, University of Manitoba, 351 Tache Ave, Manitoba, R2H 2A6, Winnipeg, Canada

Fibrogenesis & Tissue Repair 2012, 5:14  doi:10.1186/1755-1536-5-14

Published: 3 September 2012

Abstract

We are pleased to introduce a new thematic series dealing with cardiac fibrosis and its association with cardiovascular diseases. A wide variety of cardiovascular diseases are associated with cardiac fibrosis, which is now widely recognized to be not a secondary, but rather a primary contributor to cardiac dysfunction. The purpose of the current series of papers and reviews is to provide the reader with an up-to-date synopsis of the very latest research results and hypotheses that impact on cardiac fibrosis and disease.

Keywords:
Cardiac fibrosis; Cardiac fibroblasts; Myofibroblasts; Phenoconversion; Extracellular matrix