Hyaluronidase (HYAL) induced an increase in bronchoalveolar cells with a phenotype of mesenchymal stem cells. Gate 1 is a representative picture showing forward/side scatters dot-plot of bronchoalveolar fluid cells obtained from phosphate buffered saline (PBS) treatment (black contour-plot) overlaid upon HYAL exposure (grey dot-plot), as well as the gate population highlighted in red. Histograms overlays were done using the gated population highlighted in red; open histogram = isotype; grey filled histogram = PBS; red filled histogram = HYAL. The figure depicts a representative analysis from five independent experiments.
Bitencourt et al. Fibrogenesis & Tissue Repair 2011 4:3 doi:10.1186/1755-1536-4-3